3-Benzyl-3-azabicyclo[3.2...

3-Benzyl-3-azabicyclo[3.2... - Names and Identifiers

Name	3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE
Synonyms	3-Benzyl-3-azabicyclo[3.2... 4-(Boc-ami)-3,6-dichloropyridazine 3-Benzyl-3-azabicylo[3.2.1]octan-8-one 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE (1R,5S)-3-benzyl-3-azabicyclo[3.2.1]octan-8-one (1R,5S)-3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-9-ONE 3-(phenylmethyl)-3-Azabicyclo[3.2.1]octan-8-one 3-Azabicyclo[3.2.1]octan-8-one, 3-(phenylMethyl)-
CAS	83507-33-9

3-Benzyl-3-azabicyclo[3.2... - Physico-chemical Properties

Molecular Formula	C14H17NO
Molar Mass	215.29
Density	1.140±0.06 g/cm3(Predicted)
Boling Point	342.9±22.0 °C(Predicted)
pKa	7.08±0.20(Predicted)
Storage Condition	2-8°C

3-Benzyl-3-azabicyclo[3.2... - Upstream Downstream Industry

Downstream Products

tert-butyl 8-oxo-3-azabicyclo[3.2.1]octane-3-carboxylate

3-Benzyl-3-azabicyclo[3.2... - Introduction

3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE, also known as 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: White crystalline solid
-molecular formula: C15H19NO
-Molecular weight: 233.32g/mol
-Melting Point: 80-83 ℃
-Boiling point: 315 ℃
-Solubility: Soluble in ethanol, chloroform and ether

Use:
- 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE is an important organic synthesis intermediate, which can be used to synthesize a variety of bioactive compounds such as drugs, pesticides and alkaloids.
-It can also be used as a chiral inducer and catalyst.

Method:
The preparation of 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE is usually carried out by the following steps:
1. Benzaldehyde and ethyl acetate react under alkaline conditions to generate the corresponding alcohol.
2. In the presence of thionyl chloride, a nucleophilic substitution reaction was carried out with benzyl potassium bromide to generate 3-benzyl -3-azabicyclo [3.2.1] oct-8-ol.
3. Finally, 3-BENZYL-3-AZABICYCLO[3.2.1] oct-8-ol is converted to 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE by oxidation.

Safety Information:
- 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE is an organic compound, and attention should be paid to comply with laboratory safety practices and personal protective measures.
-During handling and operation, avoid inhaling its dust or spray, and avoid contact with skin and eyes.
-If exposed or inhaled, rinse immediately with plenty of water and seek medical help if necessary.
-Please operate under safe ventilation, avoid contact with flammable materials, and keep away from open flames and heat sources.

Last Update：2024-04-09 21:00:56